Four and a half years ago I came to this forum with my cancer story. I was in remission, relapsed, and had a bone marrow transplant. I'm in recovery from that now, but my liver enzymes are slightly elevated, my heart sometimes pounds and races, and my pulmonary function is impaired. I am currently taking tacrolimus, bactrim and acyclovir. I *really* want to stop taking the bactrim and acyclovir, but the doctors are adamant that they are necessary. I am also in the process of refusing vaccinations. I'm tying to figure out whether it really would be safe to stop these drugs, and what to do in their place. The acyclovir is to protect against shingles, the bactrim is for bacterial infection. The tacrolimus is an immune-suppressant.