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I don't have time to go in depth right now, but I wanted to ask, have you looked at B6 for the pyrolluria/depression? WAPF has an article about forms of B6, but I don't think it's online yet. The gist is that raw animal forms are better, and the bad forms (cooked/plant) can compete. Avocados and bananas are the exception - they're both good sources.
Magnesium and B6 are needed to make cysteine from homocysteine. Supping cysteine would help bypass that step, but your homocysteine might get really high - a risk factor for midline defects and blood clots among other things.
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